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Modafinil is an analeptic drug, prescribed for narcolepsy, obstructive sleep apnea and shift work disorder. Headache, nervousness, insomnia, agitation, confusion, personality disorders, tremor, anxiety; GI disturbances; hypertension, palpitations, tachycardia; angioedema; psychosis, depression, mania, abnormal LFTs. May increase metabolism of ciclosporin, oral contraceptives. The mechanism of modafinil is unknown but it appears to exert its stimulant effects by reducing GABA-mediated neurotransmission. Absorption: Well absorbed from the GI tract oral ; peak plasma concentrations after hr. Excretion: Mainly via urine History of psychosis, depression, mania. Modafinil mg Brands in India

Modafinil, sold under the brand name Provigil among others, is a central nervous system CNS stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. While it has seen off-label use as a purported cognitive enhancer to improve wakefulness, in animal and human studies the research on its effectiveness for this use is not conclusive. Modafinil's side effects include headaches, anxiety, and nausea. Serious side effects in high doses include delusions, unfounded beliefs, paranoia, irrational thought, and transient depression, possibly due to its effects on dopamine receptors in the brain, as well as allergic reactions. The amount of medication used should be adjusted in those with kidney problems, as this medication has markedly increased side effects during renal insufficiency. It is not recommended in those with an arrhythmia, significant hypertension, or left ventricular hypertrophy.

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