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Fenfluramine, sold under the brand name Fintepla, is a serotonergic medication used for the treatment of seizures associated with Dravet syndrome and Lennox—Gastaut syndrome. Side effects of fenfluramine in people treated for seizures phentermine to buy in uk decreased appetite, somnolence, sedation, lethargy, diarrhea, constipation, abnormal echocardiogram, fatigue, malaise, asthenia, ataxia, balance disorder, gait disturbance, increased blood pressure, drooling, excessive salivation, fever, upper respiratory tract infection, vomiting, appetite loss, weight loss, falls, and status epilepticus. Fenfluramine is indicated for the treatment of seizures associated with Dravet syndrome and Lennox—Gastaut syndrome in people age two and older. The most common adverse reactions in people with seizures include decreased appetite; drowsiness, sedation and lethargy; diarrhea; constipation; abnormal echocardiogram; fatigue or lack of energy; ataxia lack of coordination, balance disorder, gait disturbance trouble with walking ; increased blood pressure; drooling, salivary hypersecretion saliva overproduction ; pyrexia fever ; upper respiratory tract infection; vomiting; decreased weight; risk of falls; and status epilepticus. The distinctive valvular abnormality seen with fenfluramine is a thickening of the leaflet and chordae tendineae. One mechanism used to explain this phenomenon involves heart valve serotonin receptors, which are thought to help regulate growth.
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Phenylpropanolamine PPA is a sympathomimetic agent which is used as a decongestant and appetite suppressant. In veterinary medicine, it is used to control urinary incontinence in dogs. There are four optical isomers of PPA: dextro- and levo-norephedrine, and dextro- and levo-norpseudoephedrine. Exogenous compounds in this family are degraded too rapidly by monoamine oxidase to be active at all but the highest doses. In Canada, it was withdrawn from the market on 31 May PPA acts primarily as a selective norepinephrine releasing agent.

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